Liverpool captain Steven Gerrard will have a scan on Thursday after limping off with a hamstring injury in the 3-2 win over Tottenham.
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The midfielder is a major doubt for Saturday’s FA Cup fifth-round tie at Crystal Palace (17:30 GMT).
It is another midfield setback for manager Brendan Rodgers after losing Lucas Leiva to a groin injury in the same match.
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Gerrard, 34, will leave Liverpool to join Los Angeles Galaxy in the summer.
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The problem could not have come at a worse time for the Reds with six games in 19 days, including both legs of their Europa League round-of-32 tie with Turkish side Besiktas and Premier League matches against top-four sides Southampton and Manchester City.
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“Unfortunately, he felt his hamstring towards the end of the game and he is having a scan this morning and we are just waiting for results to come back,” Liverpool assistant manager Colin Pascoe said.
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“Hopefully the scans won’t show too much but as we’ve not got the results I can’t say too much.”
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Forward Raheem Sterling is another injury worry after missing the midweek game with a foot injury but Pascoe hopes he will be fit for the weekend.
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“We are monitoring Raheem,” he said. “He missed a game the other night but we will see how he is.”
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